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The name '"Marlboro"' was registered in the US in 1908 although no cigarette was marketed under this name until 1923

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Making Tobacco Bright: Creating an American Commodity, 16171937 (Johns Hopkins University Press

adults reached an estimated 14 percent in 2017, the lowest level ever

Informed consent was obtained from all participants being included in the study

The guidance has sparked criticism from harm-reduction experts who argue that it introduces more confusion than clarity