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Likewise, in murine macrophages, the activated 7nAChR can mediate Jak2-STAT3 activation and then can induce the phosphorylation of STAT3, which subsequently downregulates pro-inflammatory cytokines (e.g., IL6, IL12, and TNF-) [133]

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After injuring his knee for the second time at age 19, his athletic career ended

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Department of Health and Human Services [HHS]) broad authority to regulate the manufacturing, marketing, and sale of tobacco products, including cigarettes, cigarette tobacco, roll-your-own tobacco, and smokeless tobacco products (see Box 2-1 for highlights from the Tobacco Control Act)