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Over the years, observations on smoking patterns have confirmed that genetics play a role in ones predisposition to smoking and nicotine addiction

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When this ideal model is compared to models using the ICD-defined smokers for adjusted and unadjusted models, many of the SNP associations appear robust to the effect of smoking (as evidenced by no difference between unadjusted and adjusted models)

A filtered version was launched in the United Kingdom in 1948, but was discontinued in 1988

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