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Tobacco components may also modify the production of cytokines or inflammatory mediators which play a role in periodontal tissue destruction

This shift is driving further investment in product development

Smoking effects The tobacco can damage the womans reproductive health and it hurts the babies, The tobacco use is linked with reduced fertility and a higher risk of the miscarriage, the early delivery (premature birth), and stillbirth

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the explanation given for this paradoxical clinical behavior is that probably smoking interferes with the inflammatory and immune response by activating endothelial and inflammatory cells to induce cytokines secretion

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