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Hartmann-Boyce, J., Chepkin, S

When taken at higher doses, nicotine enhances the effect of serotonin and reduces feelings of anxiety and stress

Nicotine induced neuro-plastic changes that contribute to nicotine addiction are triggered with initial exposure to nicotine and cause significant changes in brain physiology, structure and function, and changes in behavioral responses

Funding Research reported in this publication was supported by grant number P50CA180907 from the National Cancer Institute and the FDA Center for Tobacco Products (CTP)

Do not make him list the reasons why YOU WANT HIM TO QUIT as he needs to make the decision himself