Early observations supported that human monocytes exposed to specific flavoring chemicals such as cinnamaldehyde, vanillin, and pentane-dione, found in cinnamon, vanilla, and buttery flavor e-cigarettes, respectively, resulted in a significantly elevated proinflammatory profile [57, 58]
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The very light smokers were more likely than heavier smokers to have some college education, and were more likely to perceive smoking as carrying higher health risks
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Cigarette manufacturers use it to enhance the effects of nicotine