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International Journal of Speech-Language Pathology , 19 (4)

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Med Princ Pract 25(Suppl 2):4159 Crowley-Weber CL, Dvorakova K, Crowley C, Bernstein H, Bernstein C, Garewal H, Payne CM (2003) Nicotine increases oxidative stress, activates NF-kappaB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis

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People who smoke chronically have increased risk of having ongoing respiratory symptoms so having sputum production, airway swelling sometimes wheeze, occasionally shortness of breath so the sense is definitely there that that a lot of the effects are very similar and really the differences in the effects may be related to that dose of their frequency that people are smoking

The production technological process of the tipping paper is shown in the figure