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The probiotic formulation is prescribed in the early phase of etiotropic therapy (Lykova et al., 1999)

doi:10.5534/wjmh.190068

Black SM, Beggs JD, Hayes JD, Bartoszek A, Muramatsu M, Sakai M, Wolf CR: Expression of human glutathione S-transferases in Saccharomyces cerevisiae confers resistance to the anticancer drugs adriamycin andglutachlorambucil

We know methylcobalamin is the bioactive form of B12 and does not require hepatic conversion

Gastrointestinal studies have shown that orally administered BPC-157 exerts cytoprotective effects throughout the digestive tract, including protection against NSAID-induced gastric lesions, alcohol-induced mucosal damage, and stress-induced intestinal barrier dysfunction