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A pharmacological network for lifespan extension in Caenorhabditis elegans

Research has also examined its role in upregulating matrix metalloproteinase (MMP) activity alongside their inhibitors (TIMPs), suggesting a finely balanced role in extracellular matrix remodelling rather than simple collagen deposition

If chronic inflammation or immune dysregulation is driving the disease, as in autoimmune-related CKD, thymosin alpha-1 (TA-1) works on the immune side

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