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We know nicotine can constrict blood vessels and affect the cardiovascular system, and smoking is associated with worse skin and hair outcomes in some studies
Additional information Section Editor: Alessia Cappelli Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
The higher rates of e-cigarette use among 1113 years old suggests that the age at initiation for e-cigarette use was lower 5 as in Europe and America 21,39
Kuppens 2010)
The Institute of Medicine said the benefit to public health depends on the degree to which local and state governments change their policies. Overall, in the absence of transformative changes in the tobacco market, social norms and attitudes, or in the knowledge of patterns and causes of tobacco use, the committee is reasonably confident that raising the (minimum legal age) will reduce tobacco use initiation, particularly among adolescents 15 to 17 years of age
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