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E-cigarettes were not even under regulation by the FDAs authority until May 2016, despite having been sold in the United States since 2007

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Offshore installations, such as oil rigs, may designate a room for smoking

Randomization ensured an appropriate number of responses for each set of packs

Similarly, the limited number of studies conducted in long-term sole users of e-cigarettes have been completed in regional cohorts, where environmental factors, as well as the laws and restrictions on e-cigarette products, can vary

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