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10.1001/jama.1988.03720070025028 7

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It was also found that e-cigarette exposure does not produce significant differences in the expression of a panel of genes critical for heart development (e.g., cmlc2, tnnt2, and cx43)

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The main features of COPD are airway inflammation, remodelling and mucus retention (Vogelmeier et al., 2017), leading to limited airflow into the lungs, accompanied by wheezing, cough, difficulty in breathing, sputum production, dyspnoea, increased chest wall diameter and progressive and irreversible airway hyperresponsiveness