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The strongest are the German Orienta (nicotine 1.6mg) from the 1990s, North State (nicotine 1.7mg) produced for Finland in 1978 and the Swedish Filterless Ritz Crest (nicotine 1.9mg) from the early 1980s

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The research team found mutational signatures, or molecular fingerprints of DNA damage, in the smokers DNA, counting how many of these specific mutations were found in the different tumors

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