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Inconvenient friends, or elderly and lecturing relatives, are pronounced dreadful bores. This affectionate term, like most other Slang phrases which have their rise in a certain section of society, has spread and become of general application

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In addition, the use of amphoteric tenside sodium cocoamphoacetate causes degradation of the established biofilms and enhances the effect of metronidazole (Gottschick et al., 2016)

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