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10.1152/jn.1997.77.6.3013 J

Elife 8, e43598

Moreover, the metal nanoprodrug NPS-G-Fe produced by coordinating Fe 3+ and gallic acid (GA) with Ce6 in photoactivated Pt(IV) containing nanoprodrug and then coating with PEG-modified chondroitin sulfate (PEG-CS) can lead to iron dissociation under acidic tumor microenvironment conditions, and NPS-G-Fe can promote macrophage polarization to M1 phenotype after radiotherapy thereby enhancing anti-tumor efficacy (35)

doi: 10.1021/jf302436u 70 DuncanM

[DOI] [PMC free article] [PubMed] [Google Scholar] 153.Baumeister FA, Oberhoffer R, Liebhaber GM, et al

Phase 3 clinical trial results released in May 2026 showed participants lost up to 28.3% of their body weight over 80 weeks, making it potentially more effective than semaglutide (Ozempic and Wegovy) and tirzepatide (Zepbound and Mounjaro)