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Unlike infectious swelling, cancer-related lymph node enlargement tends to be persistent and progressive, often growing larger over time rather than shrinking

secondhand smoke is even worse

On a molecular level, relevant measurements in target tissues of smokers include changes in RNA or protein expression, somatic mutations or loss of heterozygosity, alterations in promoter methylation, and mitochondrial mutations

Furthermore, ROR co-immunoprecipitated with p53 and the interaction increased p53 reporter gene activity

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