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Cigarette manufacturers and tobacco manufacturers have used internal tobacco industry research to optimise the inclusion of pyrazines in their products

How do different nicotine strengths affect puff equivalence

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The wrong nicotine level can also lead to complications

doi: 10.1111/ans.14679 19

There wasand would remaina powerful notion that risk is largely variable and thus, most appropriately evaluated and monitored at the individual, clinical level.18 According to this logic, some people could smoke without risk to health, whereas others apparently suffered untoward and sometimes serious consequences