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Dokoupil asked Calantzopoulos, "How, after years of acknowledged deception on the part of the tobacco industry, do you convince not only regulators but the public to trust you this time when you say [e-cigarettes are] better?" "Look, it's very nice to say, 'Philip Morris, you can't believe them today because you couldn't believe them yesterday,' and so on

Both drugs also create intense psychological dependence and significantly affect levels of dopamine, a neurotransmitter associated with pleasure and reward