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The present study revealed that the component(s) other than nicotine of CSE and HTP would damage corneal epithelium through the pathway associated with intracellular iron and ferritin

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Using the values obtained in Table 4, the estimated contents (g/cigarette) of Al, As, Cd, Cu, Fe, Mn, Ni, Pb, and Zn in mainstream smoke, after accounting for the pre-existing presence of these trace metals on the control MCE membranes and the percent recovery of cigarette smoke, are listed in Table 6

Environ Sci Pollut Res 25:1045610470 Novotny TE, Zhao F (1999) Consumption and production waste: another externality of tobacco use