Early phase response (weeks 1-2) Initial responses to combination therapy typically manifest as reduced inflammation and pain at injury sites
Injection site pain, redness or swelling may occur (local inflammation)
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These protective responses have been associated with coordinated biological actions involving vascular support, regenerative signaling, and regulation of inflammatory activity, collectively contributing to enhanced tissue resilience and recovery in injury models
Vitamin B12 deficiency has been linked to neurological symptoms like head pain
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