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It is positioned as a more approachable full-flavour option compared to the heaviest commercial brands and delivers real tobacco intensity without becoming overwhelming for regular smokers

Attaching the back by myself was rather tricky and induced a couple of Tourettes Syndrome-like bouts of violent swearing

Eventually, this can lead to habit, reduced expression of receptors, higher use, and eventually, dependence

Supplementary Figure 9d: representative images from at least ten 20 fields from the two timepoints indicated for cultures from each of two donors

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