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Changes in tobacco control policies across and within US states created a natural experiment, which we were able to examine using data on 499,381 adolescents from 36 US states

There is no safe level of second-hand smoke

The parent study, which was launched in Fall 2018, examined the US vape retail environment and its impact on use among young adults from 6 metropolitan statistical areas (MSAs: Atlanta, Boston, Minneapolis, Oklahoma City, San Diego, Seattle) selected based on differences in state tobacco control efforts

These results strongly correlate with the increased oxidative stress generated in BBB endothelial cultures (see Figure 3A2) and revealing that the highest level of oxidation is in endothelial cells that are exposed to ultralow and NF cigarette smoke extracts

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