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[1] Times Newspaper 20 th August 2025 [2] [3] Times Newspaper 20 th August 2025 [4] [5] [6]

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We suggest that the rapid rise pattern of arterial blood nicotine concentration stimulates and then desensitizes autonomic nAChRs leading to disruptions of cardiac function as well as systemic and uterine hemodynamics that reduces uteroplacental blood flow, a mechanism underlying maternal smoking-associated pregnancy complications and developmental disorders