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Single-cell RNA sequencing and spatial transcriptomics are novel approaches that provide deeper insights into the cellular heterogeneity in DPN pathogenesis

The process involves more steps than preparing an injectable solution but uses similar principles

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3 Immunohistochemistry of interleukin-1 (IL-1) in the dorsal root ganglion (DRG) and spinal cord (SC) at (A) 5 min (representative value of phase 1) and (B) 35 min (representative value of phase 2) Graph (bottom) represents the number of immunostained cells in the DRG and SC (mean SD)