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Furthermore, studies showed nicotine interacts with brain monoamine transporter such as serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET), a major transporter system for CNS drugs (Table 1)
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However, neither GLO nor IQOS rules out the potential damage to health , although logically, the former should be slightly safer by its lower heating temperature of almost 100 C
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Although there is evidence for atrial fibrosis and remodeling of connexin-protein expression contributing to the pre-existing atrial substrate in poAF patients in some reports (127), this is not a universal finding (148)