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Smoking decreases functional diversity of the epithelium To understand the effect of smoking habit, we first examined whether genes previously reported to be differentially expressed between current and never-smokers, based on bulk RNA-seq from bronchial airway epithelial brushings 9 , were similarly affected in each cell type independently

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"Variation in Prevalence and Burden of Chronic Obstructive Pulmonary Disease by State and Insurance Type in the United States"

Gutteridge JM, Halliwell B