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2) Results of the cDNA microarray performed by the research team in a previous study, revealed that expression of the growth hormone receptor genes was significantly increased in the tendon fibroblasts treated with BPC 157

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First, we sought to identify a medium that would support assembloid formation, that is, the culture of all three cell types: hepatocytes, cholangiocytes/ductal cells and portal mesenchyme without overgrowth of any of them, we tested several media and found that a minor adaptation of the DM medium used for h-HepOrgs differentiation without A8301 (assembloid medium) supported culture of the three cell types while preventing their overgrowth

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This modulation may influence the expression of key inflammatory mediators such as tumor necrosis factor- (TNF-), thereby improving the wound microenvironment in diabetes (134)