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The steroid is an anti-inflammatory medication that is able to temporarily stop the inflammation within the joint

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Whereas amylin acts via the amylin receptor, a complex of CALCR and one of three receptor activity modifying proteins (RAMP13), cagrilintide binds the amylin receptor and CALCR with similar potency

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1 In REDEFINE 1, cagrilintide provided clinically meaningful weight loss, with an average body weight reduction of 11.8% compared to 2.3% with placebo after 68 weeks, if all participants adhered to treatment