PMID: 38729448 Cell Mol Life Sci Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin
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Shifting to every-other-day administration during weeks 46 reduces cumulative receptor occupancy and slows further desensitization while still maintaining therapeutic plasma IGF-1 LR3 levels, extending the effective anabolic window by 12 weeks compared to continuous daily dosing that plateaus completely by week 5
For observational studies, quality evaluation focused on study design appropriateness, methodological rigor, sample size adequacy, and consistency of findings
Angiogenesis 23 , 5574 (2020)