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The Connectivity Map analysis cited by Campbell, Pickart, and Margolina found that GHK affects approximately 31 percent of analyzed human genes, with the net pattern resetting age-shifted gene expression toward younger profiles 8 9

Kirkman, D

demonstrated that palmitoylation of AEG-1 Cys75 was able to inhibit signals such as inflammation, lipid accumulation, and motility and their upstream pathways in hepatocytes, suggesting that aberrant AEG-1 palmitoylation may be present in MASH, and that the specific mechanism needs to be further investigated (160)

Yi B, Nguyen MC, Won MH, Kim YM, Ryoo S