22 February 2022
However, medical supervision helps ensure optimal dosing, appropriate monitoring, and safety when using multiple compounds simultaneously
No data exists on developmental effects, and cell proliferating properties raise theoretical concerns
Novo Nordisk is testing an IL6 inhibitor, Ziltivekimab, which cut hsCRP levels by ~80-90% in the phase 2 trial: The phase 3 trial is measuring the hard outcomes: cardiovascular death, myocardial infarction, or stroke, in people with established cardiovascular disease, chronic kidney disease, and persistent inflammation
10.1016/j.sbi.2016.10.015 639 UverskyV
They released their findings in 2013 in a paper published by the National Bureau of Economics