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The World Anti-Doping Agency (WADA) has banned its use in sports7

Most states set the legal limit of BAC at .08% for both males and females

This conformational restriction prevents the peptide from adopting flexible substrate orientations that proteases require for efficient cleavage

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NICE guidelines for weight management emphasise evidence-based interventions including dietary modification, increased physical activity, behavioural therapy, and in appropriate cases, pharmacological treatments (such as orlistat or semaglutide) or bariatric surgery

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