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There have been concerns expressed about increasing use of ECs among adolescents and its possible impact on subsequent smoking uptake

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In vitro , e-cigarette aerosol created from low concentration (3 mg/mL) base nicotine e-liquid induced a polarization towards M1 in monocyte-derived macrophages(21), which is consistent with the pro-M1 phenotyping seen in the human subjects study using similar e-liquids(29)

She said that moving the legal age to 21 allows more time for brains to mature, resulting in less neurological susceptibility to addiction

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