and acute, subacute, and chronic) shows a definitive rescue of disabled neuromuscular junctions (both phase I and phase II) and counteracts failure of nerve-to-muscle transmission [81]
Vidal-Alaball J, Butler C, Cannings-John R et al
The specific protocol used in any individual case depends on the patient's clinical picture and is determined by the provider
Dosing recommendations suggest therapeutic use at less than 2 mg/kg, while potential toxic effects may occur at levels exceeding 5 mg/kg
After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency
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