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This concept, however, also implies that the uncoupling of eNOS is mediated by ONOO and would invariably require a primary superoxide anion source such as the Nox, xanthine oxidase or mitochondria
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In addition, in vitro studies have shown that recombinant TTR amyloid aggregates are internalized by human cardiac fibroblasts, which subsequently secrete IL-6 and IL-8, providing mechanistic evidence that TTR aggregates can trigger inflammatory responses in cardiac cells [77]
Treff NR et al (2017) Levels of trophectoderm mitochondrial DNA do not predict the reproductive potential of sibling embryos
