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Knocking down ACTL6A had no impact on NRF2 expression (Supplementary Fig 6h)

Mitochondrial dysfunction, oxidative stress, and neuroinflammation: intertwined roads to neurodegeneration

Mastroberardino Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made

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The major part of the flux is carried by the low affinity transporter, which has sigmoidal kinetics with a V max in the range 9001400 M/hr, a K m of approximately 3000 M, and a Hill coefficient of approximately 3 [3436]

After 24 hours of patch use, average blood glutathione levels rose by more than 300 percent over baseline