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A general dosage might be 50 to 100 mg per week for women and 100 to 200 mg per week for men for certain conditions."Deca 250": The term "Deca 250" typically refers to the 250 mg concentration of the injection

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Participants were randomized 1:1:1 to retatrutide 9 mg weekly, retatrutide 12 mg weekly, or placebo, and treated for 68 weeks

More specifically, it interacts with serotonin receptors (5-HT1A/5-HT2), dopamine receptors, GABA balance, and the nitric oxide system