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Next-generation mass spectrometry and bioinformatics are enabling untargeted, large-scale metabolite inventories, supporting hypothesis-driven research and regulatory applications

Sciex Analyst software version 1.7.1 (TripleTOF) was used for data acquisition

On the contrary, SB has no effect on cyclin E and cdk2, which are gene products associated with G1 phase of the cell cycle (Lee et al., 2004d)

Neurological deficit was assessed using the NIHSS on admission and after 24 h and 3-month mRS (with good outcome defined as 03)

Between the most popular inbred strains are A/J, BALB/cByJ (BALB), BTBR T+Itpr3tf/J (BTBR), C58/J (C58), and 129S1/SvImJ mice, which exhibit lack of sociability, as compared to inbred mouse strains with high sociability, such as C57BL/6J (B6) and FVB/NJ mice

Results: 2581 stroke survivors were assessed at 3-months and 918 (35.6%) had depression