547 Although macrophages are not yet proven to be capable of metallotoxicity against pathogenic Neisseria species, it has been shown that these immune cells can enhance zinc accumulation in cytoplasm and phagocytic vesicles through ZIPs
By inhibiting NNMT, research suggests that 5-Amino-1MQ may help enhance NAD+ availability, which has downstream implications in metabolic health and mitochondrial function
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doi: 10.1016/j.ymthe.2017.05.012