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B12 deficiency may result in neurological issues, anemia, poor bone density, and age-related macular degeneration of the eye

Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements

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These receptors are coupled with Gs-proteins that transmit a stimulatory signal to adenylyl cyclase to generate cyclic AMP (cAMP)

At Lifeline Primary Care, we frequently help these patients manage their B12 levels through tailored injection therapy

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