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30 732 44 Sykes AJ, Wlodek C, Trickey A, Clayton GL, Oakley A

PhotobiomodulationUnderlying mechanism and clinical applications

In vivo , FTO knockdown significantly elevates YTHDF2 expression in the striatum of PD mice, inhibits m 6 A demethylation of BAP1 and reduces BAP1 expression, upregulates SLC7A11 expression, decreases -Syn, MDA, Fe 2+ , and 4-HNE levels, suppresses neuronal ferroptosis and disruptions in the amino acid antioxidant system, and promotes dopaminergic neuronal survival in PD mice (Li et al., 2025c)

Several hypotheses have been proposed for the pathogenesis of depression