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Methods Computer-aided molecular design, synthesis, and characterization All the computer-aided molecular design studies were performed in SZMAP/GamePlan 37 and vBrood 38 modules in OpenEye software and Molecular Operating Environment, MOE 39

Rosenthal, S

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We then discuss the possible aetiology of ALS and illustrate how strong risk factors including environmental toxins such as BMAA and heavy metals can functionally behave to promote protein aggregation and disturb copper metabolism that likely drives this vicious cycle in sporadic ALS

Staphylococcus aureus binds to the n-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis