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While Hinge alone did alter base-line synaptic transmission it attenuated HGF and Dihexa increases in AMPA-frequencies (Figure 13 A and B)

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The dose is increased over time to allow for smooth acclimation and reduced side effects

This disruption allows senescent cells to undergo apoptosis, making FOXO4-DRI a promising senolytic agent for anti-aging and therapeutic applications

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