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JCI Insight 6 , e153732 (2021)

Additionally, the key pathological features of RA, such as fibroblast-like synoviocyte (FLS) proliferation, hyperplastic synovial lining, articular cartilage injury, bone destruction, reduced joint space, swollen inflamed synovial membrane, and angiogenesis, are highlighted

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Reference List Betterman, Dr

Symptoms Patients generally report the feeling of a deep ache directly in the front and top of the shoulder

In some embodiments, an otic high viscosity formulation or device is administered as monotherapy for treatment of an otic disease or condition described herein