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Realizing this potential will require sustained collaboration across dermatology, pharmacology, toxicology, and pharmaceutical science to ensure the safe, efficacious, and scalable clinical application of flavonoid-based interventions

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The solvent system should be chosen by the investigator based on the assay design, compatibility requirements, and institutional protocol

These reviews and case studies highlight that while injections promise skin lightening and detox support, they can carry very real risks that outweigh their cosmetic appeal

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