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For the construction of the metE mutant, the AES -which contained a Kan R cassette and the GFP gene optimized for its expression in mycobacteria (eGFP) (Supplementary Note 1)- was synthesized by GenScript

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The primary efficacy end point was a change in Disease Activity Index (DAI) over the treatment period

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If you've had these labs completed within the past 24 months, you may not need labs ordered during your initial consultation, but this decision will be made by your provider