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We refer to a prior review for the pharmacology of LAC [28]

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Specifically, a dose of 200 mg/kg SAE demonstrated the most significant benefits, characterized by a marked reduction in reactive oxygen species (ROS) production, an enhancement of antioxidant defenses within the lens, a decrease in lipid peroxidation, a suppression of apoptotic processes, and an increase in cell proliferation

Because B12 is water-soluble, the excess is rapidly excreted, so sustained benefit often requires repeated dosing or correction of a deficiency

Extended 8-week protocols may be necessary for research examining maximal effects or long-term adaptations

People often take Biotin supplements for hair loss, brittle nails, and nerve damage