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[PubMed] Pickart L, et al

Gaugler JE, Potter T, Pruinelli L

In support, intravenous or intravitreous L-NAME application, given before, would aggravate the harmful effect of the major noxious procedure (i.e., ischemia by increasing intraocular pressure above systolic pressure by the infusion into the anterior chamber

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Other applications favor injection

Combinations with physical therapy for musculoskeletal injuries, with standard medical therapy for gastrointestinal conditions, or with other regenerative peptides such as growth hormone secretagogues could provide synergistic benefits