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R Cytosolic GSTs function as homodimers or heterodimers with a conserved N-terminal domain containing the GSH binding site (G-site) and a variable C-terminal domain containing the hydrophobic substrate binding site (H-site)

48 , e1194e1202 (2020)

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When the body detects these pathogens, the immune system launches a massive defensive response, releasing pro-inflammatory cytokines like IL-6 and TNF- in what is sometimes called a "cytokine storm." While this inflammatory response is necessary to destroy the virus, it comes at a steep metabolic cost