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Intracellularly, mainly in adipose tissue, its antioxidant action is limited, thus uric acid could interact with other radicals, and this could initiate a cascade of reactions to generate superoxide forms

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Depiction of the location of MTHFR 1 A single nucleotide polymorphism (SNP) in the MTHFR gene (known as the C677T variant) involves the replacement of a cytosine (C) by a thymine (T)

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